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目的评价高血压初期重复性的动态血压节律对靶器官损害的影响。方法对有重复性动态血压节律的137例患者进行高血压靶器官检查。结果根据血压节律分为勺形组(N=106)和非勺形组(N=31),非勺形组左房内径(LA)显著大于勺形组(35.7±4.0VS32.6±3.8),E/A值显著减小(0.95±0.32VS1.1±0.34);左室构型组成比方面,非勺形组正常构型者明显少于勺形组,向心性重构者或左心室肥厚者明显多于勺形组;颈总动脉内膜中层厚度(IMT)和IMT增厚发生率非勺形组均大于勺形组。结论有重复性的、持续时间较长的非勺形动态血压节律是加重心脏及大动脉损害的重要因素。
Objective To evaluate the effect of repetitive ambulatory blood pressure rhythm on target organ damage in the early stage of hypertension. Methods A total of 137 patients with repetitive ambulatory blood pressure rhythm were examined for the target organ of hypertension. Results According to the blood pressure rhythm, the left atrial diameter (LA) in non-spoon group was significantly higher than that in spoon-shaped group (35.7 ± 4.0 vs 32.6 ± 3.8) (0.95 ± 0.32VS1.1 ± 0.34). The left ventricular configuration ratio, the non-spoon shaped group of normal configuration was significantly less than the spoon-shaped group, concentric remodeling or left ventricular Hypertrophic group was significantly more than the spoon-shaped group; common carotid artery intima-media thickness (IMT) and IMT thickening incidence of non-spoon-shaped group were larger than the spoon-shaped group. CONCLUSIONS: Non-spoon-shaped ambulatory blood pressure rhythms that are repetitive and long lasting are important factors that aggravate the damage of heart and aorta.