原发性血小板减少性紫癜(简ITP)常用强的松、氨肽素或免疫抑制剂治疗。脾切除治疗虽有良效,但损伤较大,且有发生全身凶险性感染之可能。为克服这一缺点,我们和北京友谊医院协作应用经皮股动脉穿刺逆行脾动脉栓塞术,治疗1例严重ITP,获得成功,现报告如下。患者女性,19岁。10天前右前臂红色斑点逐渐增多、扩散,并渐融合成片。伴发热、鼻衄、血尿及黑便,诊断为原发性血小板减少性紫癜于1985年6月14日入院。查体:四肢皮肤散在出血点,左下肢有一6×8cm片状暗紫色淤斑,唇及口腔粘膜亦有 Primary thrombocytopenic purpura (Jane ITP) commonly used prednisone, aminopeptidin or immunosuppressive agents. Although splenectomy has good effect, but greater damage, and the risk of systemic infection may occur. To overcome this shortcoming, we and Beijing Friendship Hospital in collaboration with percutaneous femoral artery puncture retrograde splenic artery embolization, the treatment of one case of severe ITP, was successful, are as follows. Patient female, 19 years old. 10 days ago, the right forearm gradually increased the red spots, spread, and gradually fused into tablets. With fever, epistaxis, hematuria and melena, diagnosed as primary thrombocytopenic purpura on June 14, 1985 admitted. Physical examination: limbs and skin scattered in the bleeding point, the left lower limb has a 6 × 8cm dark purple disc ecchymosis, lip and oral mucosa also