普魯卡因青霉素不耐高热,在70℃左右即开始变質,95°—105℃熔化,因此不可能在120℃消毒二小时达到灭菌目的。倘無菌操作不够严密,致使普魯卡因青霉素成品染菌而又無适当的灭菌方法,势必造成次品。因此,已污染的普魯卡因青霉素的灭菌問題是急需解决的。据文献报道,氧化乙烯杀菌力强,並对普魯卡因青霉素無损害作用,因而使用氧化乙烯灭 Prussianacin penicillin intolerance heat, began to degenerate about 70 ℃, 95 ° -105 ℃ melting, it is impossible to sterilize at 120 ℃ for two hours to achieve the purpose of sterilization. If the aseptic operation is not tight enough, resulting in procaine penicillin finished bacterial contamination without proper sterilization methods, is bound to cause defective. Therefore, the problem of sterilization of contaminated procaine penicillin is urgently needed. It is reported in the literature, strong bactericidal effect of ethylene oxide, and non-damaging effect of procaine penicillin, and thus the use of ethylene oxide off