目的观察两种药物保守治疗异位妊娠的临床疗效。方法将138例异位妊娠患者随机分成两组:观察组70例予MTX(50mg/m2)单次肌注。7d复查血β-HCG下降<15%,则再次同法肌注1次,最多不超过3次,同时空腹口服米非司酮100mg,每日2次,共3d。对照组单用MTX肌注、不加用米非司酮。观察两组疗效。结果观察组治愈率90%、对照组治愈率73.5%。结论MTX+米非司酮治疗异位妊娠有协同作用,对于能早期就诊、早期诊断的异位妊娠患者能明显提高治愈率。 Objective To observe the clinical efficacy of conservative treatment of two drugs in ectopic pregnancy. Methods 138 cases of ectopic pregnancy were randomly divided into two groups: observation group of 70 patients given MTX (50mg / m2) a single intramuscular injection. 7d review of blood β-HCG decreased <15%, then once again with the law muscle injection, up to no more than 3 times, while oral administration of mifepristone 100mg, 2 times a day for a total of 3d. Control group with MTX intramuscular injection, without adding mifepristone. The two groups were observed. Results The cure rate was 90% in the observation group and 73.5% in the control group. Conclusion MTX + mifepristone has synergistic effect on ectopic pregnancy, and the cure rate of ectopic pregnancy patients with early diagnosis and early diagnosis can be significantly improved.