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目的探讨药物洗脱支架在急性心肌梗死(AMI)急诊冠脉介入治疗中应用的安全性和有效性。方法选择2002-11~2004-11在深圳市人民医院心内科收治的77例AMI患者,均在起病12h内给予急诊经皮冠状动脉介入治疗(PCI),按介入治疗时使用的支架不同分为两组:雷帕霉素药物洗脱支架组(38例)和普通支架组(39例)。结果所有77例病人PCI均获得成功。雷帕霉素药物洗脱支架组38支梗死相关血管的38处病变置入了38个支架;普通支架组39支梗死相关血管的39处病变置入了39个支架。两组病人的PCI后造影情况、临床情况差异无显著性。结论CypherTM雷帕霉素药物洗脱支架应用于急性心肌梗死血栓性病变是安全的和有效的。
Objective To investigate the safety and efficacy of drug-eluting stents in the emergency PCI of acute myocardial infarction (AMI). Methods A total of 77 AMI patients admitted to the Department of Cardiology, Shenzhen People’s Hospital from 2002-11 to 2004-11 were given emergency percutaneous coronary intervention (PCI) within 12 hours of onset. According to the different scaffolds used in interventional therapy Two groups: rapamycin-eluting stent group (38 cases) and conventional stent group (39 cases). Results All 77 patients achieved PCI successfully. Thirty-eight stents were placed in 38 lesions of the infarcted-related blood vessels in the rapamycin-eluting stent group; 39 stents were placed in 39 lesions of 39 infarct-related vessels in the common stent group. Two groups of patients after PCI angiography, clinical differences were not significant. Conclusion The CypherTM rapamycin-eluting stent is safe and effective for the treatment of thrombotic lesions in acute myocardial infarction.