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对饮水氟浓度分别为0.59mg/L、0.90mg/L、1.59mg/L、1.90mg/L、3.37mg/L的五组人群用氯胺T氧化法测血清羟脯氨酸(HYP);用赖氏法测血清谷丙转氨酶(SGPT);用4—氨基安替比林法测血清碱性磷酸酶(AKP)。结果:五组人群HYP均值依次为0.081mg/ml、0.210mg/ml、0.158mg/ml、0.179mg/ml;五组人群AKP均依次为2.27金氏单位/d1,10.50金氏单位/d1,12.21金氏单位/dl,9.69金氏单位/dl,7.5金氏单位/dl;五组人群SGPT均值依次为19.61卡门氏单位/dl、17.35卡门氏单位/dl、20.22卡门氏单位/dl、22.71卡门氏单位/dl、11.22卡门氏单位/dl。上述结果提示:五组人群HYP均值随水氟浓度的增高而增高;当水氟浓度在1.59mg/L以上时,AKP活性随水氟浓度增加而随低;当水氟浓度在0.59mg/L~3.37mg/L范围内,暂未看出对SGPT的影响。
The drinking water fluoride concentrations were 0.59mg / L, 0.90mg / L, 1.59mg / L, 1.90mg / L, 3.37mg / L of the five groups with chloramine T oxidation of serum hydroxyproline Acid (HYP). Serum alanine aminotransferase (SGPT) was determined by Lai’s method. Serum alkaline phosphatase (AKP) was measured by 4-aminoantipyrine. Results: The mean of HYP in five groups were 0.081mg / ml, 0.210mg / ml, 0.158mg / ml and 0.179mg / ml respectively. The AKP of five groups were 2.27 units / d1,10 .50 Gold unit / d1, 12.21 Gold unit / dl, 9.69 Gold unit / dl, 7.5 Gold unit / dl; five groups of SGPT mean 19.61 Carmen units / dl , 17.35 Carmen unit /dl,20.22 Carmen unit /dl,22.71 Carmen unit /dl,11.22 Carmen unit / dl. The above results suggest that the mean of HYP in five groups increased with the increase of water fluoride concentration. When the water fluoride concentration was above 1.59mg / L, the AKP activity decreased with the increase of water fluoride concentration. When the water fluoride concentration was 0.59mg /L~3.37mg/L range, temporarily not seen SGPT impact.