我们知道,有许多例子是药物进入体内经酶的作用后,由药物母体——即前体药物(Prodrug)中释放出有药理作用的活性物质,前体药物的典型例子就是百浪多息。在体内,它转化成磺胺药。早期,人们是无意识的制造了前体药物,但近来,则是有目的地设计能在作用部位释放出有药效的前体药物。如将氨苄青霉素与(口匹)呋酸酯化成(口匹)呋氨苄青霉 We know there are many examples of the pharmacological effects of the drug released into the body through the action of enzymes after the drug has released its pharmacologically active substance from the drug parent Prodrug. A typical example of a prodrug is psyllium. In the body, it is converted to sulfa drugs. In the early days, people unconsciously made prodrugs, but more recently they have been purposefully designed to release pharmacologically acceptable prodrugs at the site of action. Such as ampicillin and (mouth horses) formate esterification (oral) Fu Furui Fu Penicillium