The degradation of phenol in aqueous solution with the combination of microwave and ozone (MW/O_3) was studied with laboratory-scale experiments. Effects of ozone dose, pH value, initial phenol concentration and reaction temperature on the reaction kinetics were investigated. In all cases, the degradation of phenol follows a pseudo-first-order kinetics relation. MW/O_3 combined technology is favorable for enhancing the removal efficiency of phenol, with the enhancement factor of the first-order kinetics constant being around 3. 6. Experimental results showed that the synergetic effect of MW/O_3 combined technology was obvious and up to 99 % of phenol was removed after 30 min reaction with initial phenol concentration of 100 mg · L~(-1), ozone dose of 1. 1 mg · Min~(-1), pH value of 9-11, and reaction temperature of 25℃.