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ＩＬ１２通过ＩＦＮγ起到激活特异性和非特异性的抗肿瘤效应的作用。ＩＬ１８（ＩＦＮγ诱导因子，ＩＧＩＦ）则有加强ＩＦＮγ的释放和抑制ＩＬ１０作用，并能提高患有ＭｅｔｈＡ肿瘤的ＢＡＬＢ／Ｃ鼠的存活率。而两种因子的协同作用能更为有效地参与全身性...
IL-12 plays a role in activating specific and non-specific anti-tumor effects through IFN-γ. IL-18 (IFN-γ-inducing factor, IGIF) enhances the release of IFN-γ and inhibits IL-10, and it can increase the survival rate of BALB/C mice with MethA tumors. The synergy of the two factors can more effectively participate in systemic ...