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目的对九江市健康婴儿血清中TTV感染情况进行检测 ,以期阐明TTV在婴儿中的感染状况及传播途径。方法用改良UTRPCR法 ,检测婴儿血清中TTVDNA。结果 :用改良UTRPCR检测 86例婴儿中 5 1例 (5 3.5 % )TTVDNA为阳性 ,其中 <30日龄、1～ 6月龄和 7～ 12月龄婴儿中 ,TTVDNA检出率分别为 0、33.3%、95 .0 %。结论九江市95 %的半岁以上婴儿感染有TT病毒 ,婴儿中TTV的原发感染可能是出生后从环境中获得 ,并且随其年龄增长感染逐渐增多。
Objective To detect the status of TTV infection in healthy infants in Jiujiang City in order to clarify the infection status and transmission of TTV in infants. Methods The modified UTRPCR method was used to detect TTVDNA in infant serum. Results: TTVDNA was positive in 51 cases (53.5%) of 86 infants detected by modified UTRPCR. The detection rate of TTVDNA was 0 in <30 days old, 1 ~ 6 months old and 7 ~ 12 months old infants, 33.3%, 95.0%. Conclusion Ninety-five percent of infants aged over six months in Jiujiang are infected with TT virus. The primary infection of TTV in infants may be obtained from the environment after birth and gradually increase with age.