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目的 观察小脑顶核电刺激 (FNS)对急性脑梗死患者血清神经元特异性稀醇化酶 (NSE)和S10 0的影响 ,探讨该治疗的康复疗效。方法 6 0例急性脑梗死的患者随机分为电刺激小脑治疗组 (FNS组 ,30例 )和常规治疗对照组 (30例 ) ,分别观察其治疗前后患者血清NSE和S10 0 水平的动态变化及神经功能缺损评分情况。结果 FNS组与对照组治疗前神经功能缺损评分及血清NSE、S10 0 水平无显著差异 (P >0 .0 5 ) ,治疗后两组患者血清NSE、S10 0 水平和神经功能缺损评分均有下降 ,但FNS组下降更显著 ,差异有显著性(P <0 .0 1)。结论 小脑顶核电刺激可降低急性脑梗死患者血清NSE、S10 0 水平 ,有利于促进神经功能恢复。
Objective To investigate the effects of fastigial nucleus stimulation (FNS) on serum neuron specific digestive enzyme (NSE) and S10 0 in patients with acute cerebral infarction (ACI) and to explore the rehabilitation effect of this treatment. Methods Sixty patients with acute cerebral infarction were randomly divided into electrical stimulation of cerebellum (FNS group, 30 cases) and routine treatment control group (30 cases). The changes of serum NSE and S10 0 in patients with acute cerebral infarction were observed. Neurological deficit scores. Results There was no significant difference in the scores of neurological deficits, serum NSE and S10 0 levels between the FNS group and the control group before treatment (P> 0.05), and the serum NSE, S10 0 levels and neurological deficit scores of both groups decreased after treatment , But the FNS group decreased more significantly, the difference was significant (P <0.01). Conclusion Electrical stimulation of cerebellar fastigial nucleus can reduce the serum levels of NSE and S10 0 in patients with acute cerebral infarction and promote neurological function recovery.