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目的综合评价“超薄液基细胞学(TCT)—阴道镜—病理活检”三阶梯诊断在宫颈病变诊断中的应用价值。方法收集中南大学湘雅医院2007年7月-2008年3月年妇科门诊就诊患者或体检、且均行三阶梯诊断女性共562例,均有性生活史,并进行统计分析。结果经χ2检验,TCT与病理活检结果比较,P>0.05,符合率为82.3%,两者阳性结果接近。阴道镜检与病理活检结果比较,P<0.05,符合率58.0%,两者有差别。TCT联合阴道镜与病检结果比较,P>0.05,符合率85.2%,优于单一TCT或阴道镜检查。宫颈病变趋向年轻化。结论三阶梯诊断能提高宫颈病变的检出率,有利于早预防、早诊断、早治疗,达到有效防治宫颈癌的目的。
Objective To evaluate the value of three-step diagnosis in diagnosis of cervical lesions by ultra-thin liquid-based cytology (TCT) -columnoscopy-pathology biopsy. Methods A total of 562 female patients were enrolled in the gynecological outpatient department of Xiangya Hospital of Central South University from July 2007 to March 2008, and 562 women were diagnosed as having a three-step ladder. All of them had sex life history and conducted statistical analysis. Results χ2 test, TCT and pathological biopsy results, P> 0.05, the coincidence rate was 82.3%, the positive results of both approaches. Colposcopy and pathological biopsy results, P <0.05, coincidence rate of 58.0%, there are differences between the two. TCT combined with colposcopy and pathological results, P> 0.05, coincidence rate of 85.2%, better than a single TCT or colposcopy. Cervical lesions tend to be younger. Conclusion Three-step diagnosis can improve the detection rate of cervical lesions, which is good for early prevention, early diagnosis and early treatment and achieve the purpose of effective prevention and treatment of cervical cancer.