目的:探讨慢性酒精中毒导致智能损害的影响因素。方法:以神经心理测验分数为因变量,以年龄、饮酒量等15个因素为自变量对92例慢性酒精中毒导致智能损害的患者进行多元回归分析。结果:92例患者智能损害与饮酒史总年数、开始酒精依赖期饮酒量、首次戒酒时年龄、开始饮酒时饮酒量、异常脑电图、神经系统合并症、出现精神障碍时年龄、开始酒精依赖时年龄有关(P<005)。结论:开始酒精依赖期饮酒量、饮酒史总年数等因素与智能损害相关,且饮酒史总年数、出现精神障碍时年龄、开始酒精依赖期饮酒量分别是影响总智商、语言智商、操作智商、记忆总商数的主要因素。 Objective: To investigate the influencing factors of intellectual impairment caused by chronic alcoholism. Methods: Neuropsychological test scores as the dependent variable, age, alcohol consumption and other 15 variables as independent variables in 92 patients with chronic alcohol poisoning caused by intellectual impairment in multiple regression analysis. Results: The total number of years of mental impairment and alcohol drinking in 92 patients, the alcohol consumption during the period of alcohol dependence, the age at the first alcohol abstinence, the alcohol consumption at the beginning of drinking, abnormal EEG, neurological complications, age at onset of mental disorders, Dependent on age (P <005). Conclusion: The factors such as total alcohol consumption, the total number of years of drinking history, and total number of years of alcohol consumption are related to the impairment. The total years of drinking history, age at onset of mental disorders, Memory of the main factors of the total number.