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在民间,小决明(Cassia tora)叶一直作为抗风湿药使用。为证实民间的传统用法,采用不同诱导剂引起的大鼠炎症模型和肉芽肿试验,评价了小决明叶提取物的抗炎活性,并与保泰松进行了比较。实验材料:取小决明叶打粉后用90％甲醇提取,提取液经减压、浓缩后,得到半固体物质,并以不同浓度悬浮在吐温80和水中备用。实验方法:采用角叉菜胶、右旋糖酐、组胺和5-
In folk, Cassia tora leaves have been used as anti-rheumatic drugs. In order to confirm the traditional folk usage, the anti-inflammatory activity of the extract of Cassia obtusifolia was evaluated using a rat model of inflammation induced by different inducers and a granuloma test, and compared with phenylbutazone. Experimental materials: After the powdered cassia leaves were extracted with 90% methanol, the extracts were decompressed and concentrated to obtain semi-solid substances, which were suspended in Tween 80 and water at different concentrations for use. Experimental method: carrageenan, dextran, histamine and 5-