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目的了解动物实验研究报告指南(ARRIVE指南)与动物实验金标准报告清单(GSPC)在兰州市动物实验研究相关人员中的知晓情况,为其有效推广提供参考依据。方法采用自行设计的问卷对兰州市医学院校教师和临床医学研究生进行调查。调查内容包括调查对象的基本信息,对ARRIVE指南、GSPC及其他医学研究报告指南的知晓情况等。采用SPSS 21.0软件进行统计分析。结果共发放调查问卷329份(包括40名教师和289名研究生),最终回收有效答卷287份。调查结果显示:ARRIVE指南和GSPC在兰州市医学院校教师和研究生中的知晓率,分别为12.5%和11.8%,且师生间知晓率无明显差异(P=0.903)。调查途径以及调查对象的年龄、学历、职业、单位均对知晓率无明显影响(P均>0.05)。调查对象知晓报告指南的主要途径为网络(33.4%)、相关论文(21.2%)和学术报告(17.4%)。结论 ARRIVE指南与GSPC在兰州市动物实验相关人员中的知晓率较低,需要采取针对性措施进行推广与普及。
Objective To understand the status quo of animal experiment research report (ARRIVE) and animal experiment gold standard report (GSPC) in relevant personnel of animal experiment research in Lanzhou, and to provide a reference for its effective promotion. Methods The self-designed questionnaire was used to investigate the teachers and clinical medical graduates of Lanzhou Medical College. The survey included basic information of the respondents, their knowledge of ARRIVE guidelines, GSPC and other guidelines for medical research reports. SPSS 21.0 software for statistical analysis. Results A total of 329 questionnaires (including 40 teachers and 289 graduate students) were distributed and 287 valid questionnaires were finally recovered. The survey results showed that the ARRIVE guidelines and GSPC awareness among teachers and postgraduates in medical schools in Lanzhou City were 12.5% and 11.8% respectively, with no significant difference between teachers and students (P = 0.903). The way of investigation as well as the age, education background, occupation and unit of the respondents had no significant effect on the awareness rate (all P> 0.05). The main ways in which respondents were aware of the reporting guidelines were online (33.4%), relevant papers (21.2%) and academic reports (17.4%). Conclusion ARRIVE guidelines and GSPC in Lanzhou animal experiments related to personnel awareness is low, need to take targeted measures to promote and popularize.