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贫血是慢性肾功能衰竭（ＣＲＦ）的严重并发症，发生率为ＣＲＦ的９７％［１］。各种血液净化技术可以延长患者生命，但均不能明显地改善贫血。其原因是血液净化技术只能解决部分肾脏排泄功能，而不能解决肾脏的内分泌功能。肾性贫血发生的中心环节是肾红细胞生成素（ＥＰＯ）
Anemia is a serious complication of chronic renal failure (CRF), with a rate of 97% of CRF [1]. Various blood purification techniques can prolong the life of patients, but none of them significantly improve anemia. The reason is that blood purification technology can only solve part of the renal excretion function, but can not solve the endocrine function of the kidney. Renal anemia is the central link of renal erythropoietin (EPO)