遗传因素是肿瘤发生的重要因素。氮—乙酰化转移酶是含氮药物和外源化学物质代谢过程中的重要酶系。本文报道了４０例肺癌病人氮—乙酰化转移酶多态现象研究。其中，７例为慢型（１７．５％），１１４４名参比学生中，２３２名为慢型（２０．３％），基因频率分别为０．４１８３和０．４５０３。两者之间无显著差异。初步认为原发性支气管肺癌与氮—乙酰化酶多态之间无联系。 Genetic factors are important factors in tumorigenesis. Nitrogen-acetyltransferases are important enzyme systems in the metabolism of nitrogenous drugs and exogenous chemicals. This paper reports on the study of N-acetyltransferase polymorphism in 40 patients with lung cancer. Among them, 7 cases were slow (17.5%), 1144 reference students, 232 were slow (20.3%), and the gene frequencies were 0.4183 and 0.4503, respectively. There is no significant difference between the two. Initially, there was no relationship between primary bronchial lung cancer and nitrogen-acetylase polymorphism.