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目的了解心肌梗死并发心源性休克患者中联合施予经皮冠状动脉介入治疗(PCI)+主动脉内球囊反搏疗法的可靠性。方法 10例心肌梗死并发心源性休克患者,施予PCI疗法+主动脉内球囊反搏疗法展开治疗,观察治疗前后肌酸激酶同工酶(CK-MB)、心肌肌钙蛋白T(c Tn T)、N-甲基-D-天冬氨酸受体(NMDA-R)、心肌肌钙蛋白I(c Tn I)、神经元特异性烯醇化酶(NSE)、左室射血分数(LVEF)、视锥蛋白样蛋白-1(VILIP-1)、左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)变化。结果治疗后,10例患者CK-MB、c Tn T、NMDA-R、c Tn I、NSE、LVEF、VILIP-1、LVESD、LVEDD水平分别为(21.39±4.36)U/ml、(0.210±0.025)ng/ml、(1.90±0.18)μg/L、(0.790±0.083)ng/ml、(59.00±5.71)μg/L、(50.68±5.73)%、(3.80±0.49)μg/L、(49.00±5.23)mm、(57.92±6.37)mm,均优于治疗前的(35.00±5.23)U/ml、(0.121±0.069)ng/ml、(0.70±0.06)μg/L、(0.316±0.047)ng/ml、(30.68±3.55)μg/L、(60.67±6.61)%、(2.06±0.18)μg/L、(40.69±4.99)mm、(49.78±6.22)mm,差异均具有统计学意义(P<0.05)。治疗过程中均无并发症出现。结论对于并发心源性休克的心肌梗死病例,联合施予PCI疗法+主动脉内球囊反搏疗法表现出可靠性强的特征,推荐选用。
Objective To investigate the reliability of percutaneous coronary intervention (PCI) + intra-aortic balloon pump in patients with myocardial infarction complicated with cardiogenic shock. Methods 10 patients with myocardial infarction complicated with cardiogenic shock were treated with PCI and intra-aortic balloon counterpulsation. The levels of creatine kinase (CK-MB), cardiac troponin T (c Tn T, NMDA-R, cTn I, NSE, left ventricular ejection fraction LVEF, VILIP-1, LVESD and LVEDD were measured. Results After treatment, the levels of CK-MB, cTnT, NMDA-R, cTnI, NSE, LVEF, VILIP-1, LVESD and LVEDD were (21.39 ± 4.36) U / ml and (59.00 ± 5.71) μg / L, (50.68 ± 5.73)%, (3.80 ± 0.49) μg / L, (1.90 ± 0.18) μg / L, ± 5.23) mm and (57.92 ± 6.37) mm respectively, which were all better than those before treatment (35.00 ± 5.23 U / ml, 0.121 ± 0.069 ng / ml and 0.70 ± 0.06 μg / (30.68 ± 3.55) μg / L, (60.67 ± 6.61)%, (2.06 ± 0.18) μg / L, (40.69 ± 4.99) mm and (49.78 ± 6.22) mm respectively, with statistical significance P <0.05). No complications occurred during the treatment. Conclusions For patients with myocardial infarction complicated by cardiogenic shock, combination therapy with PCI plus intra-aortic balloon pump therapy shows strong reliability and is recommended.