神经纤维瘤病(Neurofibromatosis,NF)根据其发病特点分为周围型(NF_1)和中央型(NF_2)两种类型。NF_2以侵犯脑神经为主,最常见者为双侧性听神经瘤。NF_1主要表现为皮肤和神经的多发性神经纤维瘤和皮肤色素斑,可发生于身体许多部位。而发生于头面部者将引起面容的严重损毁。作者曾于本世纪60年代末收治3例,兹于报道。 Neurofibromatosis (NF) is divided into two types: peripheral type (NF_1) and central type (NF_2) according to its onset characteristics. NF_2 is mainly invaded by cranial nerves, and the most common one is bilateral acoustic neuroma. NF_1 is mainly expressed as multiple neurofibromas and skin pigmented spots of the skin and nerves, which can occur in many parts of the body. The occurrence of head and face will cause serious damage to the face. The author had reported 3 cases in the late 1960s and are hereby reported.