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目的探讨性腺母细胞瘤的临床病理特点、鉴别诊断及治疗与预后。方法对2例性腺母细胞瘤的临床资料、病理形态进行分析。结果 2例患者体表特征均为女性,主要症状为无月经来潮,检查发现性腺发育不良。例1肿块直径0.4 cm,例2为1.0 cm×0.8 cm×0.5 cm大小。光镜下性腺母细胞瘤由两种细胞构成,大的生殖细胞周围散在小的性索细胞,其周边可见大量无定形的透明Call-Exner小体样结构围绕,可见散在钙化点。结论性腺母细胞瘤具有特定的临床和组织学特征,但合并其他生殖细胞肿瘤时容易漏诊,也可能误诊为其他生殖细胞肿瘤而治疗不当。
Objective To investigate the clinicopathological features, differential diagnosis, treatment and prognosis of gonadoblastoma. Methods The clinical data and pathomorphology of 2 cases of adenoblastoma were analyzed. Results The body surface features of 2 patients were all female. The main symptom was no menstrual cramps. The gonadal dysplasia was found on examination. Example 1 mass diameter 0.4 cm, Example 2 is 1.0 cm × 0.8 cm × 0.5 cm size. Light microscopic gonadoblastoma by two kinds of cells, scattered around the large germ cells in the small cord cells, visible around the large number of amorphous transparent Call-Exner body-like structure around, visible scattered calcification. Conclusions GAD has specific clinical and histological features. However, it is easy to misdiagnose when combined with other germ cell tumors and misdiagnosed as other germ cell tumors.