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目的:用Meta分析系统性地评价骨性Ⅲ类错采用正畸联合双颌手术治疗前后上气道体积的改变情况。方法:电子检索中英文数据库:Cochrane library、Embase、Pub Med、Web of Science、Wan Fang、VIP、CBM、CNKI,收集有关研究骨性Ⅲ类错采用正畸联合双颌手术治疗前后上气道体积改变情况的文献。参照Cochrane协作网提供的NOS量表对纳入文献进行质量评价,用统计学软件Rev Man 5.3对纳入文献进行统计分析。结果:共纳入9篇文献,204例研究对象。鼻咽体积、总体积变化没有统计学意义(P>0.05),口咽体积变化有统计学意义(P<0.05)。结论:对于具有阻塞性睡眠呼吸暂停低通气综合征相关危险因素的骨性Ⅲ类错患者可优先选择双颌手术,但采用正畸联合双颌手术的方式仍有发生气道狭窄的风险。
OBJECTIVE: To systematically evaluate the changes of upper airway volume in patients with skeletal Class Ⅲ malocclusion treated by orthodontic and bimaxillary surgery by Meta analysis. Methods: The Chinese and English databases were searched electronically: Cochrane Library, Embase, Pub Med, Web of Science, Wan Fang, VIP, CBM, CNKI. Volume changes in the literature. According to the NOS scale provided by the Cochrane Collaboration, the quality of the included literature was evaluated and statistical analysis of the included literature was performed using the statistical software RevMan 5.3. Results: Nine articles and 204 subjects were included. There was no significant difference in nasopharyngeal volume and total volume (P> 0.05), oropharyngeal volume was statistically significant (P <0.05). CONCLUSIONS: Bipolar surgery is the preferred choice for patients with skeletal Class Ⅲ malocclusion associated with obstructive sleep apnea-hypopnea syndrome. However, orthodontics combined with bimaxillary surgery may still lead to the risk of airway stenosis.