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环孢素Ａ(ＣｙｃｌｏｓｐｏｒｉｎｅＡ ,ＣｓＡ)是一种强效免疫抑制剂 ,系由丝状真菌茄病镰刀菌和柱孢霉菌等霉菌的代谢产物中提取分离而得的一种由十一个氨基酸组成的环化多肽 ,其作用机理主要在于它能在转录水平上抑制Ｔｈ细胞产生并释放白介素 2、4、6 (ｉｎｔｅｒｌｅｕｋ
Cyclosporine A (CsA) is a potent immunosuppressant derived from the metabolites of Fusarium solani such as Fusarium solani and Bacillus pumilus and is isolated from the metabolites of eleven amino acids Of the cyclized peptide, its main mechanism of action is that it can inhibit the transcription of Th cells and the release of interleukin 2, 4, 6 (interleukin