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目的观察米非司酮联合利凡诺对晚期妊娠引产的疗效。方法选择我院要求终止妊娠的晚期妊娠患者110例,随机分为观察组和对照组,观察组给予米非司酮常规用量及联合利凡诺50mg经羊膜腔内注射终止妊娠,对照组给予100mg利凡诺经羊膜腔内注射终止妊娠。结果两组在引产有效率及完全引产率上有明显区别,观察组明显高于对照组(P<0.01),相比对照组,观察组引产时间显著较短(P<0.01),产后出血量明显较少(P<0.01),胎盘胎膜残留发生率明显较少(P<0.01),产道损伤如宫颈裂伤发生率显著较少(P<0.01)。结论米非司酮联合利凡诺相对于单纯使用利凡诺能够明显的缩短引产时间,减少并发症和宫缩痛,对于引产成功率显著提高,值得在晚期妊娠引产中推广。
Objective To observe the efficacy of mifepristone and rivanol in induction of labor during late pregnancy. Methods One hundred and ten patients with advanced pregnancy requiring terminating pregnancy in our hospital were randomly divided into the observation group and the control group. The observation group were given conventional doses of mifepristone and 50 mg of rivanol to terminate the pregnancy via amniotic cavity injection. The control group was given 100 mg Rivanol via amniotic cavity termination of pregnancy. Results There was a significant difference between the two groups in induction of labor efficiency and complete induction of labor, the observation group was significantly higher than the control group (P <0.01), compared with the control group, the observation group was significantly shorter (P <0.01), postpartum hemorrhage (P <0.01), the incidence of residual fetal membranes was significantly lower (P <0.01), and the incidence of injuries to the birth canal was significantly lower (P <0.01). Conclusions Mifepristone combined with rivanol can significantly shorten the time of induction of labor and reduce the complications and uterine contractions compared with the simple use of rivanol. The success rate of induction of labor is significantly increased, which is worthy of promotion in the induction of labor during late pregnancy.