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目的 探讨负压封闭引流技术联合逆行隐神经营养皮瓣移植在足踝部皮肤软组织缺损中的应用及对创面愈合的影响.方法 选取2015年12月-2016年12月我院收治的80例足踝部皮肤软组织缺损患者,按照电脑随机数字法分为对照组(n=40)和观察组(n=40).对照组采用逆行隐神经营养皮瓣移植治疗,观察组在对照组基础上联合负压封闭引流治疗,采用温哥华瘢痕评分对患者创面愈合情况进行评定,比较二组临床疗效及对创面愈合的影响.结果 观察组术前准备时间、换药次数及VAS评分,均少于对照组(P＜0.05);观察组踝关节功能评分,高于对照组(P＜0.05);观察组术后15d创面色泽评分、血管分布评分、厚度评分及柔软度评分及愈合时间,均低/短于对照组(P＜0.05);二组并发症发生率比较差异有统计学意义(P＜0.05).结论 足踝部皮肤软组织缺损患者在逆行隐神经营养皮瓣移植后联合负压封闭引流治疗效果理想,能促进创面愈合,值得推广应用.“,”Objective To investigate the application of negative pressure sealing drainage combined with negative pressure neurocutaneous flap transplantation in the skin and soft tissue defect of foot and ankle and its influence on wound healing.Methods From December 2015 to December 2016,80 patients with skin and soft tissue defects in ankle and foot were treated by computer random number method and divided into control group (n =40) and observation group (n =40).The control group was received retrograde saphenous neurocutaneous flap transplantation,while retrograde saphenous neurocutaneous flap transplantation combined with vacuum sealing drainage was in the treatment of observation group.By the Vancouver scar scale were evaluated in patients with wound healing,compared 2 groups of clinical curative effect and the effect on wound healing.Results On preoperative preparation time,dressing change times and VAS scores,observation group were lower than control group (P＜0.05).The ankle joint function score of observation group was higher than that of the control group (P＜0.05);the patients in the observation group 15d wound color score,score,score of vascular distribution thickness and softness score lower than the control group (P＜0.05).The complication rate had significant difference between the two groups (P＜0.05).Conclusion Combined with negative pressure sealing drainage in the treatment of ankle skin soft tissue defect after retrograde saphenous neurocutaneous flap transplantation is ideal,can promote wound healing,and is worthy of popularization and application.