论文部分内容阅读
目的调查分析广西地区2009年~2013年新生儿先天性甲状腺功能减低症(甲低)的筛查情况,评估新生儿疾病筛查在出生缺陷干预中的重要作用。方法 2009年~2013年对广西地区938 924例新生儿干滤纸片采用时间分辨荧光法检测促甲状腺素(TSH),确诊使用化学发光法检测患儿血清中的游离T3(FT3),游离T4(FT4)以及TSH,同时进行甲状腺显影扫描。结果 2009年~2013年广西地区阳性率高,CH高发,总阳性率为1.18%,CH发病率为1/1874,高于全国平均水平。结论广西地区先天性甲状腺功能减低症阳性率、发病率高,通过加强新生儿疾病筛查工作的普及对先天性甲低患儿进行早期诊断、早期治疗,可有效地控制此种出生缺陷给社会和家庭带来的危害。
Objective To investigate the screening of congenital hypothyroidism (hypothyroidism) in Guangxi from 2009 to 2013 and evaluate the important role of neonatal screening in the intervention of birth defects. Methods From 2009 to 2013, TSH was detected in 938 924 newborn infants with dry filter paper in Guangxi by time-resolved fluorescence spectroscopy. The levels of free T3 (FT3) and free T4 FT4) and TSH, while thyroid imaging scan. Results From 2009 to 2013, the positive rate was high in Guangxi. The highest incidence of CH was 1.18%. The incidence of CH was 1/1874, which was higher than the national average. Conclusions The positive rate and incidence of congenital hypothyroidism in Guangxi area are high. The early diagnosis and early treatment of congenital hypothyroidism can be effectively controlled by strengthening the screening of neonatal diseases, which can effectively control the birth defects to the society And family harm.