论文部分内容阅读
目的观察理气活血中药治疗慢性阻塞性肺疾病急性加重患者(AECOPD)临床疗效及对血液流变学的影响。方法将60例COPD急性加重期(分级为Ⅰ~Ⅲ级)的患者随机分为治疗组和对照组各30例。对照组采用西医常规治疗,治疗组在对照组治疗的基础上,加用具有理气活血作用的中药汤剂。疗程为14天。比较两组治疗前后血液流变学的变化。结果血液流变学分析:组内比较治疗组病例治疗后全血粘度(200 1/S、30 1/S、5 1/S)有显著性差异(P<0.01),红细胞压积有明显差异(P<0.01);组间比较治疗后治疗组全血粘度(200 1/S、30 1/S)和红细胞压积较对照组有显著差异(P<0.05)。说明治疗组对血液流变学的改善优于对照组。结论理气活血中药能改善慢性阻塞性肺疾病急性加重期的临床症状及血液流变学。
Objective To observe the clinical curative effect and the hemorheology of the patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) treated by Chinese herbal medicine for regulating qi and activating blood circulation. Methods Sixty COPD patients with acute exacerbation stage (grade Ⅰ ~ Ⅲ) were randomly divided into treatment group (n = 30) and control group (n = 30). The control group was treated with conventional western medicine. The treatment group was treated with the traditional Chinese medicine decoction with the effect of regulating qi and activating blood circulation on the basis of the treatment of the control group. Treatment for 14 days. The changes of hemorheology before and after treatment were compared between the two groups. Results Hemorheological analysis: There were significant differences in the whole blood viscosity (200 1 / S, 30 1 / S, 5 1 / S) after treatment in the treatment group (P <0.01) and the hematocrit (P <0.01). After treatment, the whole blood viscosity (200 1 / S, 30 1 / S) and hematocrit in the treatment group were significantly different from those in the control group (P <0.05). The treatment group on the improvement of hemorheology better than the control group. Conclusion Liqi Huoxue Chinese medicine can improve the clinical symptoms and hemorheology of acute exacerbation of chronic obstructive pulmonary disease.