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目的探讨慢性牙周疾病与冠心病之间的关联性。方法利用医学文献搜索引擎收集1996—2011年与此相关的病例对照研究和队列研究文献,应用Meta分析软件对数据进行定量分析。结果 5篇病例对照研究和3篇队列研究被纳入,病例对照研究合并的OR值为3.00,95%可信区间为1.41～6.38,队列研究合并的RR值为1.53,95%可信区间为1.21～1.90。结论慢性牙周病有增加冠心病的危险性。
Objective To investigate the relationship between chronic periodontal disease and coronary heart disease. Methods The medical literature search engine was used to collect the relevant case-control and cohort literature from 1996 to 2011. Meta-analysis software was used to quantitatively analyze the data. Results Five case-control studies and three cohort studies were included. The case-control study combined OR was 3.00, the 95% confidence interval was 1.41 to 6.38, the RR for cohort was 1.53, and the 95% confidence interval was 1.21 ~ 1.90. Conclusion Chronic periodontal disease can increase the risk of coronary heart disease.