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目的：探讨骨肉瘤动脉内化疗栓塞术的临床疗效和病理改变。材料与方法：对３２例病理确诊的骨肉瘤做动脉内化疗栓塞术，然后行手术切除，对以上病例作术前后的临床症状、体征、实验室检查和病理的对比观察，并与１１例作全身化疗的对照组比较。结果：较之全身化疗组、动脉内化疗栓塞组的病例其临床症状和体征均明显改善，肿瘤组织坏死度明显增高。结论：用动脉内化疗栓塞治疗骨肉瘤疗效明显高于全身化疗，是手术治疗前应选择的治疗方法。
Objective: To investigate the clinical efficacy and pathological changes of intra-arterial chemoembolization for osteosarcoma. Materials and Methods: Intra-arterial chemoembolization was performed on 32 cases of osteosarcoma diagnosed pathologically, and then surgical resection was performed. The clinical symptoms, signs, laboratory examinations and pathology before and after the operation were compared with 11 cases. Comparison of the control group for systemic chemotherapy. Results: Compared with the systemic chemotherapy group and intra-arterial chemoembolization group, the clinical symptoms and signs were significantly improved, and the tumor tissue necrosis was significantly increased. Conclusion: The efficacy of intraarterial chemoembolization in the treatment of osteosarcoma is significantly higher than that of systemic chemotherapy. It is the treatment method that should be selected before surgery.