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近年来二氯有机锡(Ⅳ)含双氮配体络合物具有抗肿瘤活性的发现,不仅为人们寻找性能优良的抗癌药物开辟了新途径,而且其合成与结构的研究势必促进有机锡化学的发展。本文报道了2-(2'-吡啶基)-6-甲苯并噻唑及其二氯·二乙基合锡(Ⅳ)反应产物的谱学表征、晶体结构和抗癌活性筛选的主要结果。
In recent years, the discovery of anti-tumor activity of dichloro-organotin (IV) -containing dinitrogen ligand complexes has not only opened up new avenues for people to look for good anti-cancer drugs, but also their synthesis and structure research will promote the development of organotin Chemical development. The main results of the spectral characterization, crystal structure and anticancer activity screening of 2- (2’-pyridyl) -6-methylbenzothiazole and its dichloro-diethyltin (Ⅳ)