有机化学反应选择性一直是科学家们的重要研究课题。本文在已有经验规律的基础上归纳了择点和择面两条规则，并首次表述了新的择键规则。这三条经验规则的基础是能量最低原理。有机反应的选择性主要取决于可能产物的稳定性（热力学控制）或可能反应途径活化能之间的差异（动力学控制）。 The selectivity of organic chemistry has always been an important research topic for scientists. Based on the existing law of experience, this paper summarizes the two rules of choice and choice, and for the first time expresses the new choice of key rules. The three rules of thumb are based on the principle of lowest energy. The selectivity of the organic reaction mainly depends on the difference (kinetic control) between the stability of the possible product (thermodynamic control) or the possible activation energy of the reaction pathway.