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目的 :观察帕米膦酸二钠 (搏宁 )对恶性肿瘤骨转移的临床疗效。方法 :3 8例恶性肿瘤患者静点搏宁 60～ 90 m g/次 ,部分病例联合静脉化疗 (n=16)。结果 :搏宁对骨痛治疗的有效率为78.95 % ,联合化疗的疗效 (有效率 87.5 % )优于单用搏宁 (有效率 72 .7% )。活动能力改善有效率为84.4% ,9例血钙增高患者经治疗后血钙复常率为 77.78%。不良反应主要为发热、食欲减退、恶心、全身酸痛等。结论 :搏宁能有效地缓解骨转移疼痛及改善活动功能障碍 ,提高患者的生活质量 ,与化疗联用疗效更好
Objective: To observe the clinical effect of pamidronate disodium (Prynin) on bone metastasis of malignant tumor. Methods: 38 patients with malignant tumor were treated with Pseudodeoxynamide at 60-90 m g / time, and some cases were given intravenous chemotherapy (n = 16). Results: Prynzine treatment of bone pain rate was 78.95%, the combined effect of chemotherapy (effective rate 87.5%) is better than single Prynol (effective rate 72.7%). Active ability to improve the efficiency of 84.4%, 9 cases of hypercalcemia in patients after treatment, the rate of serum calcium was 77.78%. Adverse reactions are mainly fever, loss of appetite, nausea, body aches and so on. Conclusion: Nao Ning can effectively relieve the pain of bone metastases and improve functional dysfunction, improve the quality of life of patients, and chemotherapy combined with better efficacy