新近Stanley和Virgin着重指出B和T细胞缺陷小鼠的应用潜力,其中严重联合免疫缺陷(SCID)小鼠作为研究寄生虫的模型很有用,有望的前景之一是用于人疟原虫肝内期(LS)发育的研究。 Sacci等(1992)关于恶性疟原虫LS在SCID小鼠体内发育成功的报告,引起了人们的关注。因为它有可能提供一种加深对LS的生物学理解的手段,有助于疟原虫红细胞 Recently, Stanley and Virgin highlighted the potential of B and T cell deficient mice, of which severe combined immunodeficiency (SCID) mice are useful as models for studying parasites and one of the promising prospects is for the intrahepatic phase of human Plasmodium (LS) development of the study. Sacci et al. (1992) report on the success of Plasmodium falciparum LS in developing SCID mice. Because it is possible to provide a means of deepening the biological understanding of LS and contributing to the malaria parasite erythrocytes