有关获得性免疫缺陷综合征(AIDS)的报告,至今世界上已超过1,200例。疾病控制中心认为主要应避免与AIDS患者发生性接触;应限制男性同性恋爱的配偶数,以及采取措施排除来自血液或血浆去除术的高危险因素。已有文章描述血友病人的AIDS,并指出T-细胞群异常常见于血友病病人,这种异常常不被注意,而AIDS时则有明显的临床表现。对T细胞比例异常的病人作深入研究颇有必要,可望借以确定随后发生免疫缺陷病的危险性。有人认为AIDS仅少数发生于许多接受大量混合血浆因子Ⅷ浓缩剂治疗的血友病病人。另外,White等讨论了其它致病因素,指出本病与反复发作病毒性肝炎有关。有证据说明冷沉淀物并非为传播因素,接受浓缩剂越多则危险性越大。这些作者对自己的血友病人采取了一系列防护措施,如取消不必要的外科手术,缩 The report on Acquired Immune Deficiency Syndrome (AIDS) has so far exceeded 1,200 in the world. The Centers for Disease Control consider that sexual contact with AIDS patients should primarily be avoided; the number of males who have gay sex should be limited and measures taken to exclude high-risk factors from blood or plasma ablation. An article describing AIDS in hemophiliacs has been published, noting that abnormalities in the T-cell population are common in patients with hemophilia and that there is a clear clinical manifestation in AIDS. In-depth study of patients with abnormal T-cell ratio is necessary to determine the risk of subsequent immunodeficiency. It has been suggested that only a minority of AIDS occurs in many patients with hemophilia who are treated with a high concentration of mixed plasma factor VIII. In addition, White et al discuss other risk factors, pointing out that the disease is associated with recurrent viral hepatitis. There is evidence that cryoprecipitate is not a predisposition to transmission, and the greater the risk of receiving a concentrate, the greater the risk. These authors have taken a series of protective measures against their own hemophiliacs, such as removing unnecessary surgery and shrinking