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目的观察欣母沛治疗宫缩无力性产后出血的临床效果。方法选择2010年1月—2012年9月治疗的宫缩无力性产后出血患者48例,在使用宫缩素、米索前列醇和葡萄糖酸钙常规治疗的基础上加用欣母沛250μg肌内注射,可根据效果重复使用,间隔时间>15 min。观察产后2 h内患者出血量、用药量及药物不良反应。结果产后2 h内,出血量700~1 600 ml 28例,欣母沛用量250μg;出血量1 600~2 500 ml 18例,欣母沛用量250μg;出血量2 500~3 000 ml 1例,欣母沛用量500μg;出血量≥3 000 ml 1例,欣母沛用量1 250μg仍无效,出血症状未改善,行子宫切除术。48例患者中出现头痛2例、面部潮红2例、发热1例、血压升高1例,在降压镇静治疗后症状均缓解。结论在常规治疗基础上加用欣母沛治疗宫缩无力性产后出血,效果满意,值得临床推广。
Objective To observe the clinical effect of Xin Maopei in treating postpartum hemorrhage with uterine contractions. Methods Forty-eight patients with uterine inertia were included in our study from January 2010 to September 2012. On the basis of conventional treatment with orbital, misoprostol and calcium gluconate, , Can be reused according to the effect, the interval time> 15 min. Observed within 2 h postpartum patients with bleeding, medication and adverse drug reactions. Results Within 2 h postpartum, the bleeding amount was 700-1 600 ml in 28 cases, the dosage of Xin-Pei-Pei was 250 μg, the amount of bleeding was 1 600-2 500 ml in 18 cases, the dosage of Xin-Pei-Pei was 250 μg, the amount of bleeding was 2 500-3 000 ml in 1 case, Xin Pei Pei 500g dosage; bleeding ≥ 3000ml in 1 case, Xin Maopei dosage of 1 250μg is still invalid, the bleeding did not improve, hysterectomy. 48 cases of patients with headache in 2 cases, 2 cases of facial flushing, fever in 1 case, elevated blood pressure in 1 case, relieve the symptoms after antihypertensive treatment. Conclusion Based on the conventional treatment plus Xinmaitong treatment of uterine inertia postpartum hemorrhage, with satisfactory results, worthy of clinical promotion.