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In the case of the given design variables and constraint functions,this paper is conced with the rapid overall parameters design of trajectory,propulsion and aerodynamics for long-range ballistic missiles based on the index of the minimum take-off mass.In contrast to the traditional subsystem independent design,this paper adopts the research idea of the combination of the subsystem independent design and the multisystem integration design.Firstly,the trajectory,propulsion and aerodynamics of the subsystem are separately designed by the engineering design,including the design of the minimum energy trajectory,the computation of propulsion system parameters,and the calculation of aerodynamic coefficient and dynamic derivative of the missile by employing the software of missile DATCOM.Then,the uniform design method is used to simplify the constraint conditions and the design variables through the integration design,and the accurate design of the optimized variables would be accomplished by adopting the uniform particle swarm optimization (PSO) algorithm.Finally,the automation design software is written for the three-stage solid ballistic missile.The take-off mass of 29 850 kg is derived by the subsystem independent design,and 20 constraints are reduced by employing the uniform design on the basis of 29 design variables and 32 constraints,and the take-off mass is dropped by 1 850 kg by applying the combination of the uniform design and PSO.The simulation results demonstrate the effectiveness and feasibility of the proposed hybrid optimization technique.