Rad7 E3 Ubiquitin Ligase Attenuates Polyubiquitylation of Rpn10 and Dsk2 Following DNA Damage in &am

来源 :生物化学进展(英文) | 被引量 : 0次 | 上传用户：yanfeng_wang

【摘要】

：

During Nucleotide Excision Repair (NER) in the yeast S. cerevisiae, ubiquitylation of Rad4 is carried out by the E3 ubiquitin ligase that includes Rad7-Elc1-Cul

【作者】

：

Joseph M. Benoun Danielle Lali

【机构】

：

DepartmentofChemistryandBiochemistry

【出处】

：

生物化学进展(英文)

【发表日期】

：

2015年7期

【关键词】

：

UBIQUITIN Rad7 Rpn10 Rpn11 Dsk2 DNA Damage Response Ubiquitin Rad7 Rpn10 Rpn11 D

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During Nucleotide Excision Repair (NER) in the yeast S. cerevisiae, ubiquitylation of Rad4 is carried out by the E3 ubiquitin ligase that includes Rad7-Elc1-Cul3 and is critical to optimal NER. Rad7 E3 activity targets Rad4 for degradation by the protease

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Rad7 E3 Ubiquitin Ligase Attenuates Polyubiquitylation of Rpn10 and Dsk2 Following DNA Damage in &am

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