目的:分析卵巢过度刺激综合征(OHSS)发病早晚、病情轻重、病程长短对妊娠结局的影响。方法:对于行IVF-ET而发生中、重度OHSS的132例患者(早发型83例,晚发型49例;中度34例,重度98例;短病程103例,长病程29例;妊娠72例)临床资料进行回顾性分析。结果:①OHSS患者妊娠丢失与双胎、OHSS发病早晚、病情轻重、病程长短无显著性相关(P>0.05),但在晚发型妊娠丢失比率高于早发型、重度比率高于中度、病程长者比率高于病程短者。②早产与双胎有显著性相关(P<0.01),与OHSS发病早晚、病情轻重、病程长短无显著性相关(P>0.05)。③低体重儿与双胎有显著性相关(P<0.01),与OHSS发病早晚、病情轻重、病程长短无显著性相关(P>0.05)。结论:OHSS患者的流产比率与发病早晚、病情轻重、病程长短也无显著性相关,但在发病晚、病情重、病程长者比率略高;低体重儿、早产与双胎有显著性相关,与发病早晚、病情轻重、病程长短无相关性。 OBJECTIVE: To analyze the effect of OHSS on the pregnancy outcome in early and late onset, severity and duration of disease. Methods: 132 patients with moderate and severe OHSS undergoing IVF-ET (83 cases of early-onset, 49 cases of late-onset, 34 cases of moderate-severe OHSS and 98 cases of severe OHSS, 103 cases of short course, 29 cases of long course of disease and 72 cases of pregnancy ) Clinical data for retrospective analysis. Results: (1) There was no significant correlation between the loss of pregnancy and the incidence of OHSS (P <0.05), but the rate of loss in late pregnancy was higher than that of early onset, and the severity was longer than moderate The rate is higher than the shorter duration. (2) There was a significant correlation between preterm birth and twins (P <0.01). There was no significant correlation between the incidence of OHSS and the severity of illness and duration of OHSS (P> 0.05). (3) There was a significant correlation between low birth weight infants and twins (P <0.01). There was no significant correlation between the incidence of OHSS and severity of illness and duration of OHSS (P> 0.05). Conclusion: The rate of miscarriage in OHSS patients has no significant correlation with the onset of disease, the severity of illness and the duration of the disease. However, the rate of elderly patients with severe OHSS is slightly higher than that of the older ones. In low birth weight children, And incidence of sooner or later, severity, duration of no correlation.