十年收治40岁以上滋养细胞疾病31例,葡萄胎16例,侵蚀性葡萄胎8例,绒癌7例,恶性占49.3％。对于40岁以上滋养细胞疾病患者应早发现,早处理,并常规进行化疗和预防性子宫切除。子宫切除的优点可去除病人的危急症状和原发灶。此类患者容易造成误诊,应提高警惕,对有合并症的病人,更应如此。 Ten years of treatment of trophoblastic diseases over the age of 40 in 31 cases, 16 cases of hydatidiform mole, 8 cases of invasive hydatidiform mole, choriocarcinoma in 7 cases, malignant 49.3%. For patients over the age of 40 with trophoblastic disease should be early detection, early treatment, and routine chemotherapy and preventive hysterectomy. The advantages of hysterectomy can remove the patient’s critical symptoms and primary lesions. Such patients are likely to cause misdiagnosis, should be vigilant, for patients with comorbidity, even more so.