目前认为肾病综合征 (ＮＳ)主要是细胞免疫功能紊乱所致 ,遗传因素也参与了其发生、发展过程。有研究发现在肾脏的发育和其生理功能的发挥中 ,基因起着关键的作用 ,基因突变或缺失导致了基因产物的错误表达或相关蛋白的缺失 ,从而导致疾病的进展。本文主要从蛋白尿、脂质代谢紊 Now that the nephrotic syndrome (NS) is mainly caused by cellular immune dysfunction, genetic factors are also involved in the occurrence and development. Studies have found that genes play a key role in the development of the kidney and its physiological functions. Mutations or deletions of genes result in incorrect expression of the gene product or loss of related proteins, leading to disease progression. This article mainly from proteinuria, lipid metabolism disorders