目的　总结CT导引下经皮胸腹肿块穿刺活检的应用及技术。方法　经皮穿刺活检 10 7例胸腹肿块 ,其中胸部病变 81例 ,腹部病变 2 6例。采用 18～ 2 0G福新针或 18G同轴自动切割针 ,常规选择“垂直床面进针”、“水平床面进针”或“垂直体廓一侧进针”的进针角度。结果　一次穿刺成功率 10 0 % ,总确诊率 92 .5 %。胸部并发症发生率 11.11% ,腹部未发现明显并发症。结论　CT导引下经皮胸腹肿块穿刺活检技术简单实用 ,准确度高 ,并发症少 ,运用时应强调有明确参照物的进针角度及针具的选择 Objective To summarize the application and technique of CT guided percutaneous thoracic and abdominal mass biopsy. Methods Percutaneous biopsy of 107 cases of thoracic and abdominal mass, including 81 cases of chest lesions, 26 cases of abdominal lesions. Using 18 ~ 20G Fuxin needle or 18G coaxial automatic cutting needle, the conventional choice of “vertical bed into the needle,” “horizontal bed into the needle,” or “vertical body contour into the needle,” the needle angle. Results The successful rate of puncture was 100% and the total diagnosis rate was 92.5%. The incidence of chest complications was 11.11%, no obvious complications were found in the abdomen. Conclusion CT-guided percutaneous thoracic and abdominal mass biopsy technique is simple and practical, high accuracy, fewer complications, the use of a clear reference should be emphasized that the needle angle and needle selection