抑制性T细胞因子(TsF)如同免疫球蛋白一样,也具有结合抗原的部分,包括可变区和恒定区。在恒定区,存在表达抗原特异性的同种型决定簇。作者认为,TsF抗原结合链的恒定区决定簇与免疫球蛋白重链恒定区(Igh C)决定簇可能完全不同,前者是由抑制性T细胞第12对染色体的Igh-V基因座位右边的基因所编码产生。 Suppressive T-cell factor (TsF), like immunoglobulins, also has antigen-binding portions, including variable and constant regions. In the constant region, there is an isoform determinant that expresses antigen specificity. The authors suggest that the constant region determinant of the TsF antigen binding chain may be completely different from the Ih C determinant, the former being the gene to the right of the Igh-V locus on chromosome 12 of suppressor T cells Generated by the code.