生物标志物可以分为四大类：内剂量、生物有效量（ＤＮＡ、ＲＮＡ和蛋白质加合物）、早期生物效应和个体易感性标志物。其中内剂量及生物有效量标志物都可作为接触标志物。一、内剂量标志物所谓内剂量系指职业接触、环境接触化学物进入机体内的量。内剂量与外剂量、生物有效量 Biomarkers fall into four broad categories: internal dosages, bio-effective amounts (DNA, RNA and protein adducts), early biological effects, and individual susceptibility markers. Internal dosages and biomarkers of bioavailability can be used as contact markers. First, the internal dose markers The so-called internal dose refers to occupational exposure to environmental exposure to chemicals into the body. Internal dose and external dose, bio-effective amount