结缔组织病目前认为是一组自身免疫性疾病,临床表现复杂多变,常有多系统受累。手部病变可以是这些疾病的初发症状表现于临床,并且具有一定的特点。注意观察和识别,有助于疾病的早期诊断。本文复习有关文献仅就系统性红斑狼疮(SLE)皮肌炎(DM)、系统性硬皮病(PSS)所发生的手部病变简述如下。 Connective tissue disease is currently considered a group of autoimmune diseases, clinical manifestations of complex and volatile, often involving multiple systems. Hand lesions can be the initial symptoms of these diseases in the clinical performance, and has some characteristics. Pay attention to observation and identification, contribute to the early diagnosis of the disease. This article reviews the literature only in the context of systemic lupus erythematosus (SLE) dermatomyositis (DM), systemic scleroderma (PSS) occurred in hand lesions are summarized below.