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目的探讨新疆新源县哈萨克族居民膳食营养素摄入状况及血清叶酸与哈萨克族食管癌的关系。方法采用24 h膳食回顾法调查234名哈萨克族居民(食管癌组84例,对照组150例)各营养素的摄入情况,将结果与中国居民膳食营养素参考摄入量(DRIs)进行比较分析。全自动化学发光免疫法测定血清叶酸水平。结果食管癌组、对照组能量、蛋白质、钙、铁、钠、维生素A、硫胺素、核黄素、叶酸的摄入量分别达到DRIs的85.58%和122.83%、122.65%和169.82%、75.50%和95.78%、166.43%和226.47%、194.61%和226.06%、64.61%和91.28%、67.38%和89.57%、87.13%和100.44%、32.58%和7.53%。血清叶酸高组中食管癌组与对照组比较,差异有统计学意义(P<0.05),血清叶酸高组人群患食管癌的风险是最低组人群的0.16倍。结论哈萨克族食管癌患者铁和钠的摄入量偏高;能量、钙、维生素A、硫胺素、核黄素、维生素C的摄入量不足;叶酸的摄入量偏低;血清叶酸水平低时患食管癌的风险高。
Objective To investigate the dietary intake of Kazakh residents and the relationship between serum folic acid and Kazakh esophageal cancer in Xinjiang Xinyuan County. Methods The intake of nutrients of 234 Kazakh residents (84 cases of esophageal cancer group and 150 cases of control group) was investigated by 24 h dietary recall method. The results were compared with the reference intake of dietary nutrients (DRIs) of Chinese residents. Automatic chemiluminescence immunoassay for determination of serum folate levels. Results The intake of energy, protein, calcium, iron, sodium, vitamin A, thiamine, riboflavin and folic acid in esophageal cancer group and control group reached 85.58% and 122.83%, 122.65% and 169.82%, respectively, of DRIs, 75.50 % And 95.78%, 166.43% and 226.47%, 194.61% and 226.06%, 64.61% and 91.28%, 67.38% and 89.57%, 87.13% and 100.44%, 32.58% and 7.53% respectively. Serum folate high esophageal cancer group compared with the control group, the difference was statistically significant (P <0.05), high serum folate group risk of esophageal cancer was 0.16 times the lowest group of people. Conclusion The intake of iron and sodium in Kazakh patients with esophageal cancer is high; the intake of energy, calcium, vitamin A, thiamine, riboflavin and vitamin C is insufficient; the intake of folic acid is low; the level of serum folate Low risk of esophageal cancer is high.