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患心脏病十几年的李先生,平日心悸时服用地高辛效果不错,因此,每当他出现心悸、心慌症状时,他依照常规剂量服用地高辛。前不久,当李先生再次出现心悸症状时,依然服用了地高辛,但是服药后症状好转不明显,于是擅自增加了地高辛的剂量,服用后依然心悸、心慌,便又多次服用了地高辛,结果突然昏迷,被家人送进医院,经过急救后才脱离生命危险。医生告诉李先生,由于他擅自增加地高辛用药剂量,导致地高辛重度中毒引起昏迷,当时李先生血液中地高辛的浓度为每毫升7.6ng,而地高辛正常的血药浓度仅为每毫升0.8～2ng。这只是地高辛不良反应中的一例,地高辛作为治疗心功能不全的药物,其不良反应还有恶心、呕吐、心律失常、视觉异常等。
Lee, who has been suffering from heart disease for more than 10 years, works well with digoxin on daily palpitations. Therefore, whenever he develops heart palpitations and palpitation, he takes digoxin at the usual dosage. Not long ago, when Lee again symptoms of palpitation, still taking digoxin, but the symptoms did not improve after taking obvious, so without authorization to increase the dose of digoxin, after taking is still palpitations, palpitation, they take multiple times Digoxin, the result of a sudden coma, was sent to the hospital by his family, after emergency before out of danger. The doctor told Mr. Li that as he arbitrarily increased doses of digoxin, digoxin caused severe poisoning caused by coma, when Mr. Lee concentration of blood in the digoxin 7.6ng per ml, and digoxin normal plasma concentration only 0.8 ~ 2ng per ml. This is only one of the adverse reactions of digoxin, digoxin as a treatment of cardiac dysfunction drugs, and its adverse reactions are nausea, vomiting, arrhythmia, visual abnormalities.