高热在神经科脑部疾病中常常遇到，治疗非常棘手，一般退热药效果不佳，甚至无效，尤其在中枢性高热与脑水肿形成恶性循环时。我科自1990年以来对高颅压同时伴高热的50例病人应用冷液甘露醇进行降温，疗效较好，观介绍如下：1临床资料1．1对象50例中，男28例，女22例；年龄45～ High fever is often encountered in neurological brain diseases, the treatment is very difficult, the general antipyretics ineffective, or even invalid, especially in the central fever and cerebral edema to form a vicious cycle. Our department since 1990, high intracranial pressure accompanied by fever in 50 patients with cold liquid mannitol for cooling, the effect is better, the view is as follows: 1 clinical data 1.1 object 50 cases, 28 males and 22 females Cases; age 45 ~