盐酸特拉唑嗪分成２３，２３０，２０００和４０００ｍｇ／ｋｇ４个剂量组，灌胃给药。最高剂量组在１２7２ｈ５个时间点的微杉细胞率分别为１．８３，２．５０，１．８０，２．３３和１．６０％高中低剂量２１ｈ的微核率为１．６７，１．８３和２，１７油。空白、溶剂和阳性对照组为２．０，１．６７和３６．３３％。各剂量组分别与溶剂对照比较无显著性差异（Ｐ＞０．０５），实验结果表明盐酸特拉唑嗪未诱发小鼠骨髓细胞微核增加。 Terazosin hydrochloride was divided into 23,230,2000 and 4,000 mg / kg 4 dose groups, intragastric administration. In the highest dose group, the rates of microspor cells at 1272h were 1.83, 2.50, 1.80, 2.33 and 1.60%, respectively. 83 and 2,17 oil. Blank, solvent and positive controls were 2.0, 1.67 and 36.33%. There was no significant difference between each dose group and the solvent control (P> 0.05). The experimental results showed that the micronuclei of bone marrow cells of mice were not induced by terazosin hydrochloride.