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目的探讨C反应蛋白 (CRP)水平在急性冠状动脉综合征中的变化及其在预测预后中的价值。方法采用免疫透射比浊法测定CRP水平 ,其中不稳定型心绞痛组 5 0例 ,急性心肌梗死组 3 5例 ,正常对照组 3 0例 ,3组进行交叉对照分析。结果①不稳定型心绞痛组与急性心肌梗死组CRP水平显著高于正常对照组 (P <0 .0 1) ,且两者相比亦有明显差异 (P <0 .0 5 )。②CRP >18mg/L的患者 ,预后不良。结论CRP水平升高是急性冠状动脉综合征发生的危险因素 ,并可作为急性冠状动脉综合征患者预测预后的指标
Objective To investigate the changes of C-reactive protein (CRP) level in acute coronary syndrome and its value in predicting prognosis. Methods CRP levels were determined by immunoturbidimetry. Fifty cases of unstable angina pectoris group, 35 cases of acute myocardial infarction group, 30 cases of normal control group and three groups were analyzed by cross - control. Results ① The levels of CRP in unstable angina pectoris group and acute myocardial infarction group were significantly higher than those in normal control group (P <0.01). There was also significant difference between the two groups (P <0.05). ② CRP> 18mg / L patients, the prognosis is poor. Conclusions The elevated CRP is a risk factor for the development of acute coronary syndrome and can be used as an index to predict the prognosis of patients with acute coronary syndrome