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目的:观察复方苦参注射液对晚期肺癌合并恶性胸腔积液肿瘤患者的疗效分析。方法:选择60例晚期肺癌合并恶性胸腔积液患者,随机分为观察组和对照组,每组各30例。观察组支持治疗联合复方苦参注射液。每次40 m L,一周3次,2周为1个疗程,对照组单纯支持治疗,2个疗程后评价疗效。结果:两组比较,观察组在胸水缓解率、KPS评分方面差异有统计学意义(P<0.01)。结论:复方苦参注射液胸腔局部灌注在晚期肺癌恶性胸水患者的姑息治疗上,能控制恶性胸水,并改善生存质量。
Objective: To observe the curative effect of Fufang Kushen injection on advanced lung cancer patients with malignant pleural effusion. Methods: Sixty patients with advanced lung cancer with malignant pleural effusion were randomly divided into observation group and control group, with 30 cases in each group. Observation group supportive treatment combined with Compound Kushen injection. Each 40 m L, 3 times a week, 2 weeks for a course of treatment, the control group simply supportive treatment, evaluation of 2 courses of treatment. Results: In the two groups, the observation group had significant difference in pleural effusion response rate and KPS score (P <0.01). Conclusion: The local injection of compound Kushen injection in the palliative treatment of patients with malignant pleural effusion of advanced lung cancer can control the malignant pleural effusion and improve the quality of life.