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目的探讨声脉冲辐射力成像技术(ARFI)在非酒精性脂肪性肝病(NAFLD)中的应用价值;发现非酒精性脂肪性肝病ARFI值变化规律,为临床提供新的观察指标。方法应用ARFI技术对95例非酒精性脂肪性肝病和26例健康对照组在肝右叶4、6、8cm深度处分别进行弹性定量检测,同一深度进行5~10次ARFI检测,取平均值,分析比较各组间差异。结果肝右叶三个深度ARFI均值病例组均低于正常组(P<0.05);随着肝脏脂肪变性程度的加重,肝右叶6cm处ARFI值逐渐减低,肝右叶8cm处ARFI值明显减低。结论肝右叶三个深度ARFI均值能区分正常肝脏和非酒精性脂肪性肝病;肝右叶6、8cm处ARFI值随着脂肪肝程度的加重而减低。
Objective To investigate the value of ARFI in non-alcoholic fatty liver disease (NAFLD) and to find out the change rule of ARFI in non-alcoholic fatty liver disease, so as to provide a new observation target for clinical practice. Methods 95 cases of non-alcoholic fatty liver disease and 26 healthy control group were detected by ARFI at the depths of 4,6,8 cm in the right lobe. The ARFI test was performed 5 to 10 times at the same depth, Analysis and comparison of differences between groups. Results The ARFI values of the three groups at the right lobe were lower than those in the normal group (P <0.05). With the aggravation of hepatic steatosis, the ARFI value at the 6 cm right lobe decreased and the ARFI value at the 8 cm right lobe was significantly lower . Conclusion The three depth ARFI values of the right lobe can distinguish normal liver from nonalcoholic fatty liver disease. The ARFI value at 6 and 8 cm of right lobe decreases with the increase of fatty liver.